FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

cellular response to topologically incorrect protein

ID (Ontology)

GO:0035967 (Gene Ontology)

Definition

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein that is not folded in its correct three-dimensional structure.

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Results list data from multiple species. Choose a record type above to open its HitList.

Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_BIOLOGICAL_PROCESS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
cellular response to topologically incorrect protein (all annotations which use CV term, excluding "NOT" statements)
involved_in \| cellular response to topologically incorrect protein

Spanning Tree (Parents/Children)

response to stress
 |__cellular response to stress__________________
 |__response to topologically incorrect protein__|
cellular response to stimulus                    |
 |__cellular response to stress__________________|
                                                 cellular response to topologically incorrect protein  41 rec.
                                                  |__cellular response to misfolded protein 6 rec.
                                                  |   |__cytoplasm protein quality control by the ubiquitin-proteasome system
                                                  |   |__nuclear protein quality control by the ubiquitin-proteasome system(+) 1 rec.
                                                  |__cellular response to unfolded protein 34 rec.
                                                      |__endoplasmic reticulum unfolded protein response(+) 25 rec.
                                                      |__mitochondrial unfolded protein response 5 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	cellular response to stress response to topologically incorrect protein
Part of
Synonyms & Secondary IDs
Synonyms
	"cellular response to misfolded or unfolded protein" RELATED
Secondary IDs

External Crossreferences & Linkouts