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| Term | transcription factor AP-1 complex | ID (Ontology) | GO:0035976 (Gene Ontology) | |||||||
| Definition | A heterodimeric transcription factor complex composed of proteins from the c-Fos, c-Jun, activating transcription factor (ATF) or JDP families. The subunits contain a basic leucine zipper (bZIP) domain that is essential for dimerization and DNA binding. Jun-Fos heterodimers bind preferentially to a heptamer consensus sequence (TPA responsive element (TRE)), whereas Jun-ATF dimers bind the cyclic AMP responsive element (CRE) to regulate transcription of target genes.[ PubMed:20060892 PubMed:9069263 ] | |||||||||
| Also Known As | "Activating protein 1 complex" ; "AP-1 complex" ; "AP1 complex" (for all, see Synonyms field below) | |||||||||
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Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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transcription regulator complex_____ nuclear protein-containing complex__| RNA polymerase II transcription regulator complex |__transcription factor AP-1 complex 2 rec. |__atf1-pcr1 complex |
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| Is a | RNA polymerase II transcription regulator complex | ||
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