FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term protein-succinyllysine desuccinylase activity ID (Ontology) GO:0036055 (Gene Ontology)
Definition Catalysis of the reaction: N(6)-succinyl-L-lysyl-[protein] + NAD+ + H2O = 2''-O-succinyl-ADP-D-ribose + nicotinamide + L-lysyl-[protein].[ PubMed:22076378 ]
Also Known As "peptidyl-succinyllysine desuccinylase activity"
Comment
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       1
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 Full annotation statements 
Relevant FlyBase reports
 Genes
 protein-succinyllysine desuccinylase activity (all annotations which use CV term, excluding "NOT" statements)       1
     enables | protein-succinyllysine desuccinylase activity       1
Spanning Tree (Parents/Children)
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acyltransferase activity, transferring groups other than amino-acyl groups__
catalytic activity, acting on a protein_____________________________________|
deacylase activity__________________________________________________________|
                                                                            NAD-dependent protein lysine deacylase activity
                                                                             |__protein-succinyllysine desuccinylase activity  1 rec.
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Is a NAD-dependent protein lysine deacylase activity
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Synonyms
  • "peptidyl-succinyllysine desuccinylase activity" EXACT
    "succinyl lysine desuccinylase activity" BROAD
    "succinyllysine desuccinylase activity" BROAD
Secondary IDs
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Reactome:R-HSA-9955518 "SIRT5 desuccinylates CPS1"
RHEA:47668