FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term Derlin-1 retrotranslocation complex ID (Ontology) GO:0036513 (Gene Ontology)
Definition A protein complex that functions in the retrotranslocation step of ERAD (ER-associated protein degradation), and includes at its core Derlin-1 oligomers forming a retrotranslocation channel.[ PubMed:15215856 PubMed:16186510 ]
Also Known As"Derlin-1 complex" ; "Derlin-1 protein dislocation complex" ; "Derlin-1 retro-translocation complex" (for all, see Synonyms field below)
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Data ClassFieldDirect annotations
Genes (FBgn)GO_CELLULAR_COMPONENT
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 Derlin-1 retrotranslocation complex (all annotations which use CV term, excluding "NOT" statements)
     part_of | Derlin-1 retrotranslocation complex
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endoplasmic reticulum
 |__endoplasmic reticulum protein-containing complex___________
membrane                                                       |
 |__membrane protein complex___________________________________|
organelle membrane                                             |
 |__endoplasmic reticulum membrane_____________________________|
protein-containing complex                                     |
 |__membrane protein complex___________________________________|
 |__endoplasmic reticulum protein-containing complex___________|
nuclear outer membrane-endoplasmic reticulum membrane network  |
 |__endoplasmic reticulum membrane_____________________________|
endoplasmic reticulum subcompartment                           |
 |__endoplasmic reticulum membrane_____________________________|
                                                               Derlin-1 retrotranslocation complex  1 rec.
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Is a membrane protein complex
endoplasmic reticulum protein-containing complex
Part of endoplasmic reticulum membrane
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Synonyms
  • "Derlin-1 complex" EXACT[ PubMed:18555783 ]
    "Derlin-1 protein dislocation complex" EXACT[ PubMed:18555783 ]
    "Derlin-1 retro-translocation complex" EXACT
    "Derlin-1 retrotranslocon" EXACT
    "ERAD protein dislocation complex" EXACT[ PubMed:18555783 ]
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