FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term protein deglycase activity ID (Ontology) GO:0036524 (Gene Ontology)
Definition Catalysis of the removal of a sugar or dicarbonyl from a glycated L-arginine, L-lysine or L-cysteine residue within proteins that have been attacked and modified by glyoxal or 2-oxopropanal.[ EC:3 PubMed:14568004 PubMed:25416785 PubMed:26873906 ]
Also Known As"glyoxylase III"
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Genes (FBgn)GO_MOLECULAR_FUNCTION
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 protein deglycase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | protein deglycase activity
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catalytic activity
 |__catalytic activity, acting on a protein__________________________________________________
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds                        |
 |__hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides__|
                                                                                         protein deglycase activity  2 rec.
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Is a hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
catalytic activity, acting on a protein
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Synonyms
  • "glyoxylase III" EXACT
    "protein deglycating enzyme" RELATED[ PubMed:26873906 ]
Secondary IDs
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EC:3.5.1.124
MetaCyc:RXN-17630
MetaCyc:RXN-17632
MetaCyc:RXN-17634
RHEA:49548
RHEA:49552
RHEA:49556
RHEA:57188
RHEA:57192
RHEA:57196