FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

heme metabolic process

ID (Ontology)

GO:0042168 (Gene Ontology)

Definition

The chemical reactions and pathways involving heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.[ ISBN:0124325653 ]

Also Known As

"haem metabolic process" ; "haem metabolism" ; "heme metabolism"

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_BIOLOGICAL_PROCESS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
heme metabolic process (all annotations which use CV term, excluding "NOT" statements)
involved_in \| heme metabolic process

Spanning Tree (Parents/Children)

metabolic process
 |__pigment metabolic process________________________
tetrapyrrole metabolic process                       |
 |__porphyrin-containing compound metabolic process__|
                                                     heme metabolic process  15 rec.
                                                      |__heme biosynthetic process 14 rec.
                                                      |   |__heme A biosynthetic process 3 rec.
                                                      |   |__heme B biosynthetic process
                                                      |   |__heme C biosynthetic process
                                                      |   |__heme O biosynthetic process
                                                      |   |__regulation of heme biosynthetic process(+)
                                                      |   |__siroheme biosynthetic process
                                                      |__heme catabolic process 1 rec.
                                                      |   |__heme a catabolic process
                                                      |   |__heme B catabolic process
                                                      |   |__heme C catabolic process
                                                      |   |__heme O catabolic process
                                                      |   |__siroheme catabolic process
                                                      |__heme oxidation 1 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	porphyrin-containing compound metabolic process pigment metabolic process
Part of
Synonyms & Secondary IDs
Synonyms
	"haem metabolic process" EXACT "haem metabolism" EXACT "heme metabolism" EXACT
Secondary IDs

External Crossreferences & Linkouts
	Reactome:R-HSA-9707616 "Heme signaling"