FB2026_03 , released September 17, 2026
FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term sphingolipid delta-4 desaturase activity ID (Ontology) GO:0042284 (Gene Ontology)
Definition Catalysis of the reaction: an N-acylsphinganine + 2 Fe(II)-[cytochrome b5] + O2 + 2 H+ = an N-acylsphing-4-enine + 2 Fe(III)-[cytochrome b5] + 2 H2O.
Also Known As "delta-4 sphingolipid desaturase activity"
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Genes (FBgn)GO_MOLECULAR_FUNCTION
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 sphingolipid delta-4 desaturase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | sphingolipid delta-4 desaturase activity
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  oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
   |__oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
       |__sphingolipid delta-4 desaturase activity  1 rec.
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Is a oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
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Synonyms
  • "delta-4 sphingolipid desaturase activity" EXACT
Secondary IDs
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EC:1.14.19.17
Reactome:R-HSA-428259 "DEGS1 dehydrogenates dihydroceramide"
RHEA:46544