FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

MHC protein binding

ID (Ontology)

GO:0042287 (Gene Ontology)

Definition

Binding to a major histocompatibility complex molecule; a set of molecules displayed on cell surfaces that are responsible for lymphocyte recognition and antigen presentation.

Also Known As

"major histocompatibility complex binding"

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

Choose a record type to view annotations for this term and its child terms. Direct annotations and full annotation statements below also provide HitList buttons.

Results list data from multiple species. Choose a record type above to open its HitList.

Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_MOLECULAR_FUNCTION

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
MHC protein binding (all annotations which use CV term, excluding "NOT" statements)
enables \| MHC protein binding

Spanning Tree (Parents/Children)

  protein binding
   |__signaling receptor binding
       |__MHC protein binding  1 rec.
           |__MHC class I protein binding
           |   |__MHC class I protein binding, via antigen binding groove
           |   |__MHC class I protein binding, via lateral surface
           |__MHC class Ib protein binding
           |   |__MHC class Ib protein binding, via antigen binding groove
           |   |__MHC class Ib protein binding, via lateral surface
           |__MHC class II protein binding
               |__MHC class II protein binding, via antigen binding groove
               |__MHC class II protein binding, via lateral surface

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	signaling receptor binding
Part of
Synonyms & Secondary IDs
Synonyms
	"major histocompatibility complex binding" EXACT "major histocompatibility complex ligand" NARROW
Secondary IDs

External Crossreferences & Linkouts