FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term sphingosine-1-phosphate phosphatase activity ID (Ontology) GO:0042392 (Gene Ontology)
Definition Catalysis of the reaction: sphingosine 1-phosphate + H2O = sphingosine + phosphate.[ PubMed:8663293 ]
Also Known As"sphingosine-1-phosphate phosphohydrolase activity" ; "SPP phosphatase activity" ; "SPPase activity"
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 sphingosine-1-phosphate phosphatase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | sphingosine-1-phosphate phosphatase activity
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  phosphatase activity
   |__lipid phosphatase activity
       |__sphingosine-1-phosphate phosphatase activity  1 rec.
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Is a lipid phosphatase activity
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Synonyms
  • "sphingosine-1-phosphate phosphohydrolase activity" EXACT
    "SPP phosphatase activity" EXACT
    "SPPase activity" EXACT
Secondary IDs
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MetaCyc:RXN3DJ-25
Reactome:R-HSA-428664 "SGPP1,2 dephosphorylate sphingoid-1-phosphates"
Reactome:R-HSA-428690 "PLPP1 dephosphorylates extracellular sphingosine-1-phosphate"
Reactome:R-HSA-428696 "PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate"
RHEA:27518