FB2026_02 , released June 18, 2026

CV Term Report

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General Information

Term

histone binding

ID (Ontology)

GO:0042393 (Gene Ontology)

Definition

Binding to a histone, any of a group of water-soluble proteins found in association with the DNA of eukaryotic or archaeal chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in gene regulation and DNA replication. They may be chemically modified (methylated, acetlyated and others) to regulate gene transcription.[ PubMed:16209651 PubMed:30212449 PubMed:9305837 ]

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Results list data from multiple species. Choose a record type above to open its HitList.

Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_MOLECULAR_FUNCTION

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
histone binding (all annotations which use CV term, excluding "NOT" statements)
contributes_to \| histone binding
enables \| histone binding

Spanning Tree (Parents/Children)

  binding
   |__protein binding
       |__histone binding  48 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	protein binding
Part of
Synonyms & Secondary IDs
Synonyms
	"histone-specific chaperone activity" RELATED
Secondary IDs

External Crossreferences & Linkouts