FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term aspartic endopeptidase activity, intramembrane cleaving ID (Ontology) GO:0042500 (Gene Ontology)
Definition Catalysis of the hydrolysis of nonterminal peptide bonds in a polypeptide chain, occurring within a membrane.[ ISBN:0198506732 ]
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       3
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Relevant FlyBase reports
 Gene Groups Genes
 aspartic endopeptidase activity, intramembrane cleaving (all annotations which use CV term, excluding "NOT" statements)       1      3
     enables | aspartic endopeptidase activity, intramembrane cleaving       --       3
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endopeptidase activity____________
aspartic-type peptidase activity__|
                                  aspartic-type endopeptidase activity
                                   |__aspartic endopeptidase activity, intramembrane cleaving  4 rec.
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Reactome:R-HSA-8863101 "SPPL2a/b cleaves TNF(1-76)"
Reactome:R-HSA-9708457 "HM13 cleaves HMOX1 dimer"