FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term phosphoric ester hydrolase activity ID (Ontology) GO:0042578 (Gene Ontology)
Definition Catalysis of the reaction: RPO-R' + H2O = RPOOH + R'H. This reaction is the hydrolysis of any phosphoric ester bond, any ester formed from orthophosphoric acid, O=P(OH)3.
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       1
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 Genes
 phosphoric ester hydrolase activity (all annotations which use CV term, excluding "NOT" statements)       1
     enables | phosphoric ester hydrolase activity       1
Spanning Tree (Parents/Children)
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  hydrolase activity
   |__hydrolase activity, acting on ester bonds
       |__phosphoric ester hydrolase activity  253 rec.
           |__diphosphoric monoester hydrolase activity 1 rec.
           |   |__(13E)-labda-7,13-dien-15-ol synthase activity
           |   |__guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity 1 rec.
           |   |__prenyl-diphosphatase activity
           |__phosphatase activity 212 rec.
           |   |__2-carboxy-D-arabinitol-1-phosphatase activity
           |   |__2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase activity
           |   |__2-phosphosulfolactate phosphatase activity
           |   |__3',5'-nucleotide bisphosphate phosphatase activity
           |   |__3-deoxy-manno-octulosonate-8-phosphatase activity
           |   |__3-phosphoglycerate phosphatase activity
           |   |__5'-deoxynucleotidase activity 1 rec.
           |   |__5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity
           |   |__10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity
           |   |__acid phosphatase activity 12 rec.
           |   |__acireductone synthase activity 1 rec.
           |   |__ADP-phosphoglycerate phosphatase activity
           |   |__alkaline phosphatase activity 14 rec.
           |   |__alkylacetylglycerophosphatase activity
           |   |__alpha-ribazole phosphatase activity
           |   |__bisphosphoglycerate 3-phosphatase activity 2 rec.
           |   |__carbohydrate phosphatase activity(+) 6 rec.
           |   |__D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase activity
           |   |__deoxynucleotide 3'-phosphatase activity
           |   |__dihydrosphingosine-1-phosphate phosphatase activity
           |   |__dolichyl-phosphatase activity
           |   |__ecdysteroid-phosphate phosphatase activity 1 rec.
           |   |__FMN hydrolase activity
           |   |__fructose-1-phosphatase activity
           |   |__glucosylglycerol 3-phosphatase activity
           |   |__glycerol-2-phosphatase activity
           |   |__guanidinodeoxy-scyllo-inositol-4-phosphatase activity
           |   |__histidinol-phosphatase activity
           |   |__inositol phosphate phosphatase activity(+) 16 rec.
           |   |__L-phosphoserine phosphatase activity 1 rec.
           |   |__lipid phosphatase activity(+) 11 rec.
           |   |__lysophosphatidic acid phosphatase activity 1 rec.
           |   |__mannitol-1-phosphatase activity
           |   |__mannosyl-3-phosphoglycerate phosphatase activity
           |   |__methylphosphothioglycerate phosphatase activity
           |   |__monoterpenyl-diphosphatase activity
           |   |__N-acylneuraminate-9-phosphatase activity 1 rec.
           |   |__NADP phosphatase activity 1 rec.
           |   |__NADPH phosphatase activity 1 rec.
           |   |__nucleotidase activity(+) 8 rec.
           |   |__phosphatidylglycerophosphatase activity 1 rec.
           |   |__phosphatidylinositol phosphate phosphatase activity(+) 17 rec.
           |   |__phosphocholine phosphatase activity
           |   |__phosphoenolpyruvate phosphatase activity
           |   |__phosphoethanolamine phosphatase activity
           |   |__phosphoglycerate phosphatase activity
           |   |__phosphoglycolate phosphatase activity
           |   |__phosphoprotein phosphatase activity(+) 109 rec.
           |   |__polynucleotide 3'-phosphatase activity 1 rec.
           |   |__polynucleotide 5'-phosphatase activity 1 rec.
           |   |__pseudouridine 5'-phosphatase activity 6 rec.
           |   |__pyridoxal phosphatase activity
           |   |__ribitol-5-phosphatase activity
           |   |__RNA 2',3'-cyclic phosphatase activity 1 rec.
           |   |__RNA 2'-phosphatase activity 1 rec.
           |   |__sedoheptulose-bisphosphatase activity
           |   |__sn-glycerol 1-phosphatase activity
           |   |__sn-glycerol 3-phosphatase activity 1 rec.
           |   |__sorbitol-6-phosphatase activity
           |   |__streptomycin-6-phosphatase activity
           |   |__thiamine phosphate phosphatase activity
           |__phosphoric diester hydrolase activity 39 rec.
           |   |__7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity
           |   |__[acyl-carrier-protein] phosphodiesterase activity
           |   |__alkylglycerophosphoethanolamine phosphodiesterase activity
           |   |__C-type glycerophospholipase activity(+) 6 rec.
           |   |__CMP-N-acylneuraminate phosphodiesterase activity
           |   |__cyclic-guanylate-specific phosphodiesterase activity
           |   |__cyclic-nucleotide phosphodiesterase activity(+) 9 rec.
           |   |__D-type glycerophospholipase activity(+) 2 rec.
           |   |__dolichylphosphate-glucose phosphodiesterase activity
           |   |__dolichylphosphate-mannose phosphodiesterase activity
           |   |__glucose-1-phospho-D-mannosylglycoprotein phosphodiesterase activity
           |   |__glycerol-1,2-cyclic-phosphate 2-phosphodiesterase activity
           |   |__glycerophosphocholine cholinephosphodiesterase activity
           |   |__glycerophosphocholine phosphodiesterase activity 6 rec.
           |   |__glycerophosphodiester phosphodiesterase activity 1 rec.
           |   |__glycerophosphoinositol glycerophosphodiesterase activity
           |   |__glycerophosphoinositol inositolphosphodiesterase activity
           |   |__GPI-mannose ethanolamine phosphate phosphodiesterase activity 1 rec.
           |   |__phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands
           |   |__phosphodiesterase I activity
           |   |__phosphoribosyl 1,2-cyclic phosphate 1,2-diphosphodiesterase activity
           |   |__phosphoribosyl 1,2-cyclic phosphate phosphodiesterase activity
           |   |__protein adenylylhydrolase activity 1 rec.
           |   |__RNA 2',3'-cyclic 3'-phosphodiesterase activity
           |   |__serine-ethanolaminephosphate phosphodiesterase activity
           |   |__sphingomyelin phosphodiesterase activity(+) 6 rec.
           |   |__tyrosyl-DNA phosphodiesterase activity(+) 1 rec.
           |   |__tyrosyl-RNA phosphodiesterase activity
           |__phosphoric triester hydrolase activity
           |   |__aryldialkylphosphatase activity
           |__triphosphoric monoester hydrolase activity 1 rec.
               |__deoxynucleoside triphosphate hydrolase activity
               |__dGTPase activity 1 rec.
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Is a hydrolase activity, acting on ester bonds
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