FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term xenobiotic transmembrane transporter activity ID (Ontology) GO:0042910 (Gene Ontology)
Definition Enables the directed movement of a xenobiotic from one side of a membrane to the other. A xenobiotic is a compound foreign to the organism exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 Genes
 xenobiotic transmembrane transporter activity (all annotations which use CV term, excluding "NOT" statements)
     enables | xenobiotic transmembrane transporter activity
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  transporter activity
   |__transmembrane transporter activity
       |__xenobiotic transmembrane transporter activity  5 rec.
           |__3-hydroxyphenylpropionic acid transmembrane transporter activity
           |__ABC-type xenobiotic transporter activity 5 rec.
           |   |__ABC-type bacteriocin transporter activity
           |__bacteriocin transmembrane transporter activity
           |   |__ABC-type bacteriocin transporter activity
           |   |__colicin transmembrane transporter activity(+)
           |__benzoate transmembrane transporter activity
           |__methotrexate transmembrane transporter activity
           |__microcin transmembrane transporter activity
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Is a transmembrane transporter activity
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Synonyms
  • "drug transmembrane transporter activity" RELATED
    "drug transporter activity" RELATED
    "multidrug efflux pump activity" RELATED
    "multidrug transporter activity" RELATED
    "multidrug, alkane resistant pump activity" RELATED
    "xenobiotic transporter activity" RELATED
Secondary IDs
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Reactome:R-HSA-5625574 "Defective SLC22A18 does not exchange extracellular organic cations for cytosolic H+"
Reactome:R-HSA-597628 "SLC22A18 exchanges extracellular organic cations for cytosolic H+"
Reactome:R-HSA-9911512 "AcrA:AcrB:TolC transports antibiotics from the cytosol to the periplasm"
Reactome:R-HSA-9911517 "MdfA transports tetracyclines from the cytosol to the periplasmic space"
Reactome:R-HSA-9913106 "TetB exports tetracyclines"
Reactome:R-HSA-9913128 "TetA exports tetracyclines"
Reactome:R-HSA-9913437 "Pef exports fluoroquinolones"
Reactome:R-HSA-9913672 "OqxA exports fluoroquinolones"
Reactome:R-HSA-9914089 "MdtE:MdtF:TolC exports beta-lactams to the periplasm"
Reactome:R-HSA-9931163 "Gdx dimer exports cationic aromatics to periplasm"
Reactome:R-HSA-9931565 "EmrE dimer exports xenobiotics to periplasm"