FB2026_03 , released September 17, 2026
CV Term Report
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Term positive regulation of canonical NF-kappaB signal transduction ID (Ontology) GO:0043123 (Gene Ontology)
Definition Any process that activates or increases the frequency, rate or extent of a canonical NF-kappaB signaling cascade.
Also Known As"activation of I-kappaB kinase/NF-kappaB cascade" ; "positive regulation of I-kappaB kinase/NF-kappaB cascade" ; "positive regulation of I-kappaB kinase/NF-kappaB signaling" (for all, see Synonyms field below)
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Genes (FBgn)GO_BIOLOGICAL_PROCESS
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 positive regulation of canonical NF-kappaB signal transduction (all annotations which use CV term, excluding "NOT" statements)
     involved_in | positive regulation of canonical NF-kappaB signal transduction
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canonical NF-kappaB signal transduction
 |__regulation of canonical NF-kappaB signal transduction_____
positive regulation of signal transduction                    |
 |__positive regulation of intracellular signal transduction__|
regulation of intracellular signal transduction               |
 |__regulation of canonical NF-kappaB signal transduction_____|
 |__positive regulation of intracellular signal transduction__|
                                                              positive regulation of canonical NF-kappaB signal transduction  6 rec.
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Is a regulation of canonical NF-kappaB signal transduction
positive regulation of intracellular signal transduction
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Synonyms
  • "activation of I-kappaB kinase/NF-kappaB cascade" EXACT
    "positive regulation of I-kappaB kinase/NF-kappaB cascade" EXACT
    "positive regulation of I-kappaB kinase/NF-kappaB signaling" EXACT
    "stimulation of I-kappaB kinase/NF-kappaB cascade" NARROW
    "up regulation of I-kappaB kinase/NF-kappaB cascade" EXACT
    "up-regulation of I-kappaB kinase/NF-kappaB cascade" EXACT
    "upregulation of I-kappaB kinase/NF-kappaB cascade" EXACT
Secondary IDs
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Reactome:R-HSA-937039 "IRAK1 recruits IKK complex"