FB2026_03 , released September 17, 2026
CV Term Report
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Term negative regulation of canonical NF-kappaB signal transduction ID (Ontology) GO:0043124 (Gene Ontology)
Definition Any process that stops, prevents, or reduces the frequency, rate or extent of a canonical NF-kappaB signaling cascade.
Also Known As"down regulation of I-kappaB kinase/NF-kappaB cascade" ; "down-regulation of I-kappaB kinase/NF-kappaB cascade" ; "downregulation of I-kappaB kinase/NF-kappaB cascade" (for all, see Synonyms field below)
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Genes (FBgn)GO_BIOLOGICAL_PROCESS
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 negative regulation of canonical NF-kappaB signal transduction (all annotations which use CV term, excluding "NOT" statements)
     involved_in | negative regulation of canonical NF-kappaB signal transduction
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canonical NF-kappaB signal transduction
 |__regulation of canonical NF-kappaB signal transduction_____
negative regulation of signal transduction                    |
 |__negative regulation of intracellular signal transduction__|
regulation of intracellular signal transduction               |
 |__regulation of canonical NF-kappaB signal transduction_____|
 |__negative regulation of intracellular signal transduction__|
                                                              negative regulation of canonical NF-kappaB signal transduction  3 rec.
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Is a regulation of canonical NF-kappaB signal transduction
negative regulation of intracellular signal transduction
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Synonyms
  • "down regulation of I-kappaB kinase/NF-kappaB cascade" EXACT
    "down-regulation of I-kappaB kinase/NF-kappaB cascade" EXACT
    "downregulation of I-kappaB kinase/NF-kappaB cascade" EXACT
    "inhibition of I-kappaB kinase/NF-kappaB cascade" EXACT
    "negative regulation of I-kappaB kinase/NF-kappaB cascade" EXACT
    "negative regulation of I-kappaB kinase/NF-kappaB signaling" EXACT
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