FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term 3'-5' DNA helicase activity ID (Ontology) GO:0043138 (Gene Ontology)
Definition Unwinding a DNA helix in the direction 5' to 3', driven by ATP hydrolysis.[ EC:5 ]
Also Known As "3' to 5' DNA helicase activity" ; "ATP-dependent 3' to 5' DNA helicase activity" ; "ATP-dependent 3'-5' DNA helicase activity"
Comment
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION      13
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 3'-5' DNA helicase activity (all annotations which use CV term, excluding "NOT" statements)       1     13
     contributes_to | 3'-5' DNA helicase activity       --       6
     enables | 3'-5' DNA helicase activity       --       7
Spanning Tree (Parents/Children)
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helicase activity______________________
ATP-dependent activity, acting on DNA__|
                                       DNA helicase activity
                                        |__3'-5' DNA helicase activity  15 rec.
                                            |__single-stranded 3'-5' DNA helicase activity 2 rec.
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Is a DNA helicase activity
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Synonyms
  • "3' to 5' DNA helicase activity" EXACT
    "ATP-dependent 3' to 5' DNA helicase activity" EXACT
    "ATP-dependent 3'-5' DNA helicase activity" EXACT
Secondary IDs
hide External Crossreferences & Linkouts
EC:5.6.2.4
Reactome:R-HSA-167097 "HIV Promoter Opening: First Transition"
Reactome:R-HSA-174438 "Formation of the Flap Intermediate on the C-strand"
Reactome:R-HSA-75949 "RNA Polymerase II Promoter Opening: First Transition"
Reactome:R-HSA-9613490 "Unwinding of DNA for the nascent HIV-1 transcript: Second Transition"
Reactome:R-HSA-9613494 "Unwinding of DNA for the Nascent Transcript: Second Transition"
Reactome:R-HSA-9613497 "Unwinding DNA for the nascent transcript"
Reactome:R-HSA-9613498 "Unwinding of DNA for the nascent HIV-1 transcript"
Reactome:R-HSA-9684118 "ERCC3-facilitated RNA Pol II backtracking in TC-NER"