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| Term | ATP-binding cassette (ABC) transporter complex | ID (Ontology) | GO:0043190 (Gene Ontology) | |||||||
| Definition | A complex for the transport of metabolites into and out of the cell, typically comprised of four domains; two membrane-associated domains and two ATP-binding domains at the intracellular face of the membrane, that form a central pore through the plasma membrane. Each of the four core domains may be encoded as a separate polypeptide or the domains can be fused in any one of a number of ways into multidomain polypeptides. In Bacteria and Archaebacteria, ABC transporters also include substrate binding proteins to bind substrate external to the cytoplasm and deliver it to the transporter.[ PubMed:11421269 PubMed:15111107 ] | |||||||||
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Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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ATPase dependent transmembrane transport complex plasma membrane protein complex |
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