FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term insulin receptor substrate binding ID (Ontology) GO:0043560 (Gene Ontology)
Definition Binding to an insulin receptor substrate (IRS) protein, an adaptor protein that bind to the transphosphorylated insulin and insulin-like growth factor receptors, are themselves phosphorylated and in turn recruit SH2 domain-containing signaling molecules to form a productive signaling complex.[ PubMed:12829233 ]
Also Known As "insulin receptor substrate [protein] binding" ; "IRS [protein] binding" ; "IRS binding"
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       1
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 Genes
 insulin receptor substrate binding (all annotations which use CV term, excluding "NOT" statements)       1
     enables | insulin receptor substrate binding       1
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   |__protein binding
       |__insulin receptor substrate binding  1 rec.
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Synonyms
  • "insulin receptor substrate [protein] binding" EXACT
    "IRS [protein] binding" EXACT
    "IRS binding" EXACT
Secondary IDs
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