FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

Ku70:Ku80 complex

ID (Ontology)

GO:0043564 (Gene Ontology)

Definition

Heterodimeric protein complex composed of a 70 kDa and a 80 kDa subunit, binds DNA through a channel formed by the heterodimer. Functions in DNA double stranded break repair, chromosome maintenance, transcription regulation, V(D)J recombination, and activation of DNA-PK.[ PubMed:12518983 ]

Also Known As

"Ku70:Ku80 heterodimer"

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_CELLULAR_COMPONENT

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
Ku70:Ku80 complex (all annotations which use CV term, excluding "NOT" statements)
part_of \| Ku70:Ku80 complex

Spanning Tree (Parents/Children)

nucleus_____________________
protein-containing complex__|
                            nuclear protein-containing complex
                             |__Ku70:Ku80 complex  3 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	nuclear protein-containing complex
Part of
Synonyms & Secondary IDs
Synonyms
	"Ku70:Ku80 heterodimer" EXACT
Secondary IDs

External Crossreferences & Linkouts