FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term dihydrolipoamide branched chain acyltransferase activity ID (Ontology) GO:0043754 (Gene Ontology)
Definition Catalysis of the reaction: N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + 2-methylpropanoyl-CoA = N(6)-[(R)-S(8)-2-methylpropanoyldihydrolipoyl]-L-lysyl-[protein] + CoA. In addition to transferring the 2-methylpropanoyl group when acting on the oxoacid corresponding with valine, this activity also transfers the 3-methylbutanoyl and S-2-methylbutanoyl groups when acting on the oxo acids corresponding with leucine and isoleucine.
Also Known As"dihydrolipoamide branched chain transacylase activity" ; "enzyme-dihydrolipoyllysine:2-methylpropanoyl-CoA S-(2-methylpropanoyl)transferase activity"
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Genes (FBgn)GO_MOLECULAR_FUNCTION
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 dihydrolipoamide branched chain acyltransferase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | dihydrolipoamide branched chain acyltransferase activity       --
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  acyltransferase activity
   |__acyltransferase activity, transferring groups other than amino-acyl groups
       |__dihydrolipoamide branched chain acyltransferase activity  2 rec.
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Is a acyltransferase activity, transferring groups other than amino-acyl groups
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Synonyms
  • "2-methylpropanoyl-CoA:enzyme-6-N-(dihydrolipoyl)lysine:S-(2-methylpropanoyl)transferase activity" RELATED[ EC:2 ]
    "2-methylpropanoyl-CoA:enzyme-N6-(dihydrolipoyl)lysine:S-(2-methylpropanoyl)transferase activity" RELATED[ EC:2 ]
    "dihydrolipoamide branched chain transacylase activity" EXACT
    "dihydrolipoyl transacylase activity" RELATED[ EC:2 ]
    "dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity" NARROW
    "enzyme-dihydrolipoyllysine:2-methylpropanoyl-CoA S-(2-methylpropanoyl)transferase activity" EXACT
Secondary IDs
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EC:2.3.1.168
MetaCyc:2.3.1.168-RXN
RHEA:18865
RHEA:84647
RHEA:84651