FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term endoplasmic reticulum quality control compartment ID (Ontology) GO:0044322 (Gene Ontology)
Definition A subcompartment of the endoplasmic reticulum in which proteins with improper or incorrect folding accumulate. Enzymes in this compartment direct proteins with major folding problems to translocation to the cytosol and degradation, and proteins with minor folding problems to the ER, to interact with chaperon proteins.[ PubMed:11408579 ]
Also Known As"ER quality control compartment" ; "ERQC"
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Data ClassFieldDirect annotations
Genes (FBgn)GO_CELLULAR_COMPONENT
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 endoplasmic reticulum quality control compartment (all annotations which use CV term, excluding "NOT" statements)
     is_active_in | endoplasmic reticulum quality control compartment
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cellular_component
 |__cellular anatomical structure_________
cytoplasm                                 |
 |__endoplasmic reticulum_________________|
endomembrane system                       |
 |__endoplasmic reticulum_________________|
intracellular membrane-bounded organelle  |
 |__endoplasmic reticulum_________________|
                                          endoplasmic reticulum quality control compartment  1 rec.
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Is a cellular anatomical structure
Part of endoplasmic reticulum
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Synonyms
  • "ER quality control compartment" EXACT
    "ER-derived quality control compartment" RELATED
    "ERQC" EXACT
Secondary IDs
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