FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term macropinocytosis ID (Ontology) GO:0044351 (Gene Ontology)
Definition An endocytosis process that results in the uptake of liquid material by cells from their external environment by the 'ruffling' of the cell membrane to form heterogeneously sized intracellular vesicles called macropinosomes, which can be up to 5 micrometers in size.[ PubMed:14732047 ]
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Genes (FBgn)GO_BIOLOGICAL_PROCESS
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 macropinocytosis (all annotations which use CV term, excluding "NOT" statements)
     involved_in | macropinocytosis
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  endocytosis
   |__pinocytosis
       |__macropinocytosis  2 rec.
           |__extracellular exosome macropinocytosis
           |__regulation of macropinocytosis
               |__negative regulation of macropinocytosis
               |__positive regulation of macropinocytosis
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Is a pinocytosis
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Synonyms
  • "clathrin-independent pinocytosis" BROAD
    "single-organism macropinocytosis" RELATED
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