FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term nuclear pore central transport channel ID (Ontology) GO:0044613 (Gene Ontology)
Definition The central substructure of the nuclear pore complex (NPC), through which nucleocytoplasmic transport of RNAs, proteins and small molecules occurs. The central transport channel is filled with FG-nucleoporins, which form a selective barrier and provide a series of binding sites for transporter proteins. Characterized S. cerevisiae FG-nucleoporins include Nup159p, Nup145Np, Nup116p, Nup100p, Nsp1p, Nup57p, Nup49p, Nup42p, Nup53p, Nup59p/Asm4p, Nup60p and Nup1. Characterized vertebrate FG-nucleoporins include Nup214, Nup98, Nup62, Nup54, Nup58/45, NLP1, and Nup153.[ PubMed:18046406 PubMed:19524430 PubMed:20947011 PubMed:22419078 ]
Also Known As "nuclear pore central channel" ; "nuclear pore central plug" ; "nuclear pore transport channel"
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Data Class Field Records
Genes (FBgn)  GO_CELLULAR_COMPONENT       8
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 Genes
 nuclear pore central transport channel (all annotations which use CV term, excluding "NOT" statements)       8
     part_of | nuclear pore central transport channel       8
Spanning Tree (Parents/Children)
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nucleus
 |__nuclear protein-containing complex__
nuclear envelope                        |
 |__nuclear pore________________________|
protein-containing complex              |
 |__nuclear protein-containing complex__|
nuclear protein-containing complex      |
 |__nuclear pore________________________|
                                        nuclear pore central transport channel  8 rec.
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Is a nuclear protein-containing complex
Part of nuclear pore
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Synonyms
  • "karyopherin docking complex" RELATED
    "nuclear pore central channel" EXACT
    "nuclear pore central plug" EXACT
    "nuclear pore transport channel" EXACT
Secondary IDs
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