FB2026_02 , released June 18, 2026

CV Term Report

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General Information

Term

actin nucleation

ID (Ontology)

GO:0045010 (Gene Ontology)

Definition

The initial step in the formation of an actin filament, in which actin monomers combine to form a new filament. Nucleation is slow relative to the subsequent addition of more monomers to extend the filament.[ ISBN:0815316194 ]

Also Known As

"actin filament nucleation"

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_BIOLOGICAL_PROCESS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
actin nucleation (all annotations which use CV term, excluding "NOT" statements)
involved_in \| actin nucleation

Spanning Tree (Parents/Children)

actin cytoskeleton organization____
supramolecular fiber organization__|
                                   actin filament organization
                                    |__actin nucleation  29 rec.
                                        |__'de novo' actin filament nucleation
                                        |__Arp2/3 complex-mediated actin nucleation 22 rec.
                                        |   |__regulation of Arp2/3 complex-mediated actin nucleation(+) 9 rec.
                                        |__regulation of actin nucleation 13 rec.
                                            |__negative regulation of actin nucleation(+) 4 rec.
                                            |__positive regulation of actin nucleation(+) 5 rec.
                                            |__regulation of Arp2/3 complex-mediated actin nucleation(+) 9 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	actin filament organization
Part of
Synonyms & Secondary IDs
Synonyms
	"actin filament nucleation" EXACT
Secondary IDs

External Crossreferences & Linkouts