FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term negative regulation of heart contraction ID (Ontology) GO:0045822 (Gene Ontology)
Definition Any process that stops, prevents, or reduces the frequency, rate or extent of heart contraction.
Also Known As"down regulation of heart contraction" ; "down-regulation of heart contraction" ; "downregulation of heart contraction"
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Genes (FBgn)GO_BIOLOGICAL_PROCESS
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 negative regulation of heart contraction (all annotations which use CV term, excluding "NOT" statements)
     involved_in | negative regulation of heart contraction
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negative regulation of multicellular organismal process
 |__negative regulation of blood circulation__
heart contraction                             |
 |__regulation of heart contraction___________|
regulation of blood circulation               |
 |__regulation of heart contraction___________|
 |__negative regulation of blood circulation__|
                                              negative regulation of heart contraction  3 rec.
                                               |__negative regulation of cardiac muscle contraction
                                               |   |__negative regulation of cardiac muscle cell contraction(+)
                                               |__negative regulation of heart rate 3 rec.
                                               |   |__negative regulation of heart rate by acetylcholine
                                               |   |__negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure
                                               |__negative regulation of the force of heart contraction by chemical signal
                                               |   |__negative regulation of the force of heart contraction by acetylcholine
                                               |__negative regulation of the force of heart contraction involved in baroreceptor response to increased systemic arterial blood pressure
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Is a regulation of heart contraction
negative regulation of blood circulation
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Synonyms
  • "down regulation of heart contraction" EXACT
    "down-regulation of heart contraction" EXACT
    "downregulation of heart contraction" EXACT
    "inhibition of heart contraction" NARROW
    "negative regulation of cardiac contraction" RELATED
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