FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

negative regulation of translational initiation

ID (Ontology)

GO:0045947 (Gene Ontology)

Definition

Any process that stops, prevents, or reduces the frequency, rate or extent of translational initiation.

Also Known As

"down regulation of translational initiation" ; "down-regulation of translational initiation" ; "downregulation of translational initiation"

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_BIOLOGICAL_PROCESS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
negative regulation of translational initiation (all annotations which use CV term, excluding "NOT" statements)
involved_in \| negative regulation of translational initiation

Spanning Tree (Parents/Children)

translational initiation
 |__regulation of translational initiation________
regulation of translation                         |
 |__regulation of translational initiation________|
 |__negative regulation of translation____________|
negative regulation of gene expression            |
 |__negative regulation of translation____________|
negative regulation of protein metabolic process  |
 |__negative regulation of translation____________|
                                                  negative regulation of translational initiation  17 rec.
                                                   |__negative regulation of cytoplasmic translational initiation 1 rec.
                                                   |   |__negative regulation of cap-dependent translational initiation
                                                   |   |__negative regulation of cap-independent translational initiation
                                                   |   |__negative regulation of cytoplasmic translational initiation in response to stress
                                                   |   |__negative regulation of formation of translation preinitiation complex
                                                   |__negative regulation of formation of translation initiation ternary complex
                                                   |__negative regulation of mitochondrial translational initiation
                                                   |__negative regulation of translational initiation by iron
                                                   |__negative regulation of translational initiation in response to stress 1 rec.
                                                       |__negative regulation of cytoplasmic translational initiation in response to stress
                                                       |__negative regulation of translation in response to oxidative stress
                                                       |__negative regulation of translation initiation in response to endoplasmic reticulum stress
                                                       |__negative regulation of translational initiation in response to osmotic stress
                                                       |__negative regulation of translational initiation in response to starvation

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	regulation of translational initiation negative regulation of translation
Part of
Synonyms & Secondary IDs
Synonyms
	"down regulation of translational initiation" EXACT "down-regulation of translational initiation" EXACT "downregulation of translational initiation" EXACT "inhibition of translational initiation" NARROW
Secondary IDs

External Crossreferences & Linkouts