FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term tetrahydrofolate biosynthetic process ID (Ontology) GO:0046654 (Gene Ontology)
Definition The chemical reactions and pathways resulting in the formation of tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin group.[ ISBN:0198506732 ]
Also Known As"tetrahydrofolate anabolism" ; "tetrahydrofolate biosynthesis" ; "tetrahydrofolate formation" (for all, see Synonyms field below)
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Genes (FBgn)GO_BIOLOGICAL_PROCESS
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 tetrahydrofolate biosynthetic process (all annotations which use CV term, excluding "NOT" statements)
     involved_in | tetrahydrofolate biosynthetic process
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folic acid-containing compound metabolic process
 |__folic acid-containing compound biosynthetic process__
 |__tetrahydrofolate metabolic process___________________|
modified amino acid biosynthetic process                 |
 |__folic acid-containing compound biosynthetic process__|
pteridine-containing compound biosynthetic process       |
 |__folic acid-containing compound biosynthetic process__|
                                                         tetrahydrofolate biosynthetic process  7 rec.
                                                          |__folate cycle 5 rec.
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Is a folic acid-containing compound biosynthetic process
tetrahydrofolate metabolic process
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Synonyms
  • "tetrahydrofolate anabolism" EXACT
    "tetrahydrofolate biosynthesis" EXACT
    "tetrahydrofolate formation" EXACT
    "tetrahydrofolate synthesis" EXACT
Secondary IDs
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MetaCyc:PWY-6613
MetaCyc:PWY-6614
MetaCyc:PWY2DNV-11