FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term negative regulation of insulin secretion ID (Ontology) GO:0046676 (Gene Ontology)
Definition Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of insulin.
Also Known As"down regulation of insulin secretion" ; "down-regulation of insulin secretion" ; "downregulation of insulin secretion"
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Genes (FBgn)GO_BIOLOGICAL_PROCESS
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 negative regulation of insulin secretion (all annotations which use CV term, excluding "NOT" statements)
     involved_in | negative regulation of insulin secretion
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negative regulation of peptide secretion
 |__negative regulation of peptide hormone secretion__
insulin secretion                                     |
 |__regulation of insulin secretion___________________|
negative regulation of hormone secretion              |
 |__negative regulation of peptide hormone secretion__|
regulation of protein secretion                       |
 |__negative regulation of protein secretion__________|
 |__regulation of insulin secretion___________________|
negative regulation of protein transport              |
 |__negative regulation of protein secretion__________|
regulation of peptide hormone secretion               |
 |__regulation of insulin secretion___________________|
 |__negative regulation of peptide hormone secretion__|
negative regulation of secretion by cell              |
 |__negative regulation of protein secretion__________|
                                                      negative regulation of insulin secretion  1 rec.
                                                       |__negative regulation of insulin secretion involved in cellular response to glucose stimulus
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Is a negative regulation of protein secretion
regulation of insulin secretion
negative regulation of peptide hormone secretion
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Synonyms
  • "down regulation of insulin secretion" EXACT
    "down-regulation of insulin secretion" EXACT
    "downregulation of insulin secretion" EXACT
    "inhibition of insulin secretion" NARROW
Secondary IDs
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Reactome:R-HSA-400042 "Adrenaline,noradrenaline inhibits insulin secretion"