FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term peptide-O-fucosyltransferase activity ID (Ontology) GO:0046922 (Gene Ontology)
Definition Catalysis of the transfer of an alpha-L-fucosyl residue from GDP-beta-L-fucose to the serine hydroxy group of a protein acceptor.[ EC:2 ]
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 peptide-O-fucosyltransferase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | peptide-O-fucosyltransferase activity
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catalytic activity
 |__catalytic activity, acting on a protein__
hexosyltransferase activity                  |
 |__fucosyltransferase activity______________|
                                             peptide-O-fucosyltransferase activity  2 rec.
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Is a fucosyltransferase activity
catalytic activity, acting on a protein
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Synonyms
  • "GDP-beta-L-fucose:polypeptide O-alpha-L-fucosyltransferase activity" RELATED[ EC:2 ]
    "GDP-fucose protein O-fucosyltransferase activity" RELATED[ EC:2 ]
    "GDP-fucose:polypeptide fucosyltransferase activity" RELATED[ EC:2 ]
    "GDP-L-fucose:polypeptide fucosyltransferase activity" RELATED[ EC:2 ]
Secondary IDs
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EC:2.4.1.221
MetaCyc:2.4.1.221-RXN
Reactome:R-HSA-1912349 "Fucosylation of Pre-NOTCH by POFUT1"
Reactome:R-HSA-5173192 "POFUT2 transfers fucose to TSR domain-containing proteins"