FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term ketone body biosynthetic process ID (Ontology) GO:0046951 (Gene Ontology)
Definition The chemical reactions and pathways resulting in the formation of ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone. Biosynthesis involves the formation of hydroxymethylglutaryl-CoA, which is cleaved to acetate and acetyl-CoA.
Also Known As"ketogenesis" ; "ketone body anabolism" ; "ketone body biosynthesis" (for all, see Synonyms field below)
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Genes (FBgn)GO_BIOLOGICAL_PROCESS
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 ketone body biosynthetic process (all annotations which use CV term, excluding "NOT" statements)
     involved_in | ketone body biosynthetic process       --
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lipid biosynthetic process
 |__fatty acid derivative biosynthetic process__
biosynthetic process                            |
 |__small molecule biosynthetic process_________|
small molecule metabolic process                |
 |__small molecule biosynthetic process_________|
fatty acid derivative metabolic process         |
 |__fatty acid derivative biosynthetic process__|
                                                ketone body biosynthetic process  5 rec.
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Is a small molecule biosynthetic process
fatty acid derivative biosynthetic process
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Synonyms
  • "ketogenesis" EXACT
    "ketone body anabolism" EXACT
    "ketone body biosynthesis" EXACT
    "ketone body formation" EXACT
    "ketone body synthesis" EXACT
Secondary IDs
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MetaCyc:PWY66-367
Reactome:R-HSA-77111 "Synthesis of Ketone Bodies"