FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity ID (Ontology) GO:0047015 (Gene Ontology)
Definition Catalysis of the reaction: NAD+ + 2-methyl-3-hydroxybutyryl-CoA = NADH + H+ + 2-methylaceto-acetyl-CoA.[ EC:1 ]
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       1
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 Genes
 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity (all annotations which use CV term, excluding "NOT" statements)       1
     enables | 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity       1
Spanning Tree (Parents/Children)
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  oxidoreductase activity, acting on CH-OH group of donors
   |__oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
       |__3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity  1 rec.
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Is a oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
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Synonyms
  • "(2S,3S)-3-hydroxy-2-methylbutanoyl-CoA:NAD+ oxidoreductase activity" RELATED[ EC:1 ]
    "2-methyl-3-hydroxy-butyryl CoA dehydrogenase activity" RELATED[ EC:1 ]
    "2-methyl-3-hydroxybutyryl coenzyme A dehydrogenase activity" RELATED[ EC:1 ]
    "2-methyl-3-hydroxybutyryl-CoA dehydrogenase activity" RELATED[ EC:1 ]
Secondary IDs
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EC:1.1.1.178
MetaCyc:1.1.1.178-RXN
RHEA:13281