FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term testosterone dehydrogenase (NAD+) activity ID (Ontology) GO:0047035 (Gene Ontology)
Definition Catalysis of the reaction: testosterone + NAD+ = androst-4-ene-3,17-dione + NADH.
Also Known As"testosterone 17-beta-dehydrogenase (NAD+) activity" ; "testosterone 17b-dehydrogenase activity"
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Genes (FBgn)GO_MOLECULAR_FUNCTION
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 testosterone dehydrogenase (NAD+) activity (all annotations which use CV term, excluding "NOT" statements)
     enables | testosterone dehydrogenase (NAD+) activity
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  steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
   |__17-beta-hydroxysteroid dehydrogenase (NAD+) activity
       |__testosterone dehydrogenase (NAD+) activity  1 rec.
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Is a 17-beta-hydroxysteroid dehydrogenase (NAD+) activity
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Synonyms
  • "17-beta-HSD activity" BROAD[ EC:1 ]
    "17-ketoreductase activity" BROAD[ EC:1 ]
    "17beta-HSD" RELATED[ EC:1 ]
    "17beta-hydroxysteroid:NAD+ 17-oxidoreductase activity" RELATED[ EC:1 ]
    "3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity" BROAD[ EC:1 ]
    "3alpha(17beta)-HSD" RELATED[ EC:1 ]
    "3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)" BROAD[ EC:1 ]
    "3alpha(or 17beta)-hydroxysteroid:NAD+ oxidoreductase activity" BROAD[ EC:1 ]
    "3alpha,17beta-hydroxy steroid dehydrogenase activity" BROAD[ EC:1 ]
    "testosterone 17-beta-dehydrogenase (NAD+) activity" EXACT
    "testosterone 17b-dehydrogenase activity" EXACT
    "testosterone 17beta-dehydrogenase activity" RELATED[ EC:1 ]
Secondary IDs
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EC:1.1.1.239
KEGG_REACTION:R01836
MetaCyc:TESTOSTERONE-17-BETA-DEHYDROGENASE-RXN
RHEA:14929
Wikipedia:3alpha(17beta)-hydroxysteroid_dehydrogenase_(NAD+)