FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
Help Close All Open All
General Information
Term glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity ID (Ontology) GO:0047238 (Gene Ontology)
Definition Catalysis of the reaction: D-glucuronyl-N-acetyl-1,3-beta-D-galactosaminylproteoglycan + UDP-N-acetylgalactosamine = N-acetyl-D-galactosaminyl-1,4-beta-D-glucuronyl-N-acetyl-1,3-beta-D-galactosaminylproteoglycan + UDP.[ EC:2 ]
Also Known As "glucuronyl-N-acetylgalactosaminylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity" ; "glucuronyl-N-acetylgalactosaminylproteoglycan beta-1,4-N-acetylgalactosaminyltransferase activity" ; "N-acetylgalactosaminyltransferase II activity"
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
    Results list data from multiple species. Click on a button above and use the 'Filter by species' options on the resulting HitList to retrieve species-specific data.
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       3
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity (all annotations which use CV term, excluding "NOT" statements)       1      3
     enables | glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity       --       3
Spanning Tree (Parents/Children)
Only view relationship: 
UDP-glycosyltransferase activity__
hexosyltransferase activity_______|
                                  acetylgalactosaminyltransferase activity
                                   |__glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity  4 rec.
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a acetylgalactosaminyltransferase activity
Part of
hide Synonyms & Secondary IDs
Synonyms
  • "chondroitin synthase activity" RELATED[ EC:2 ]
    "glucuronyl-N-acetylgalactosaminylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity" EXACT
    "glucuronyl-N-acetylgalactosaminylproteoglycan beta-1,4-N-acetylgalactosaminyltransferase activity" EXACT
    "N-acetylgalactosaminyltransferase II activity" EXACT
    "UDP-N-acetyl-D-galactosamine:beta-D-glucuronosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity" RELATED[ EC:2 ]
    "UDP-N-acetyl-D-galactosamine:D-glucuronyl-N-acetyl-1,3-beta-D-galactosaminylproteoglycan beta-1,4-N-acetylgalactosaminyltransferase activity" RELATED[ EC:2 ]
    "uridine diphosphoacetylgalactosamine-chondroitin acetylgalactosaminyltransferase II activity" RELATED[ EC:2 ]
Secondary IDs
hide External Crossreferences & Linkouts
EC:2.4.1.175
MetaCyc:RXN-16325
Reactome:R-HSA-1971482 "The addition of GalNAc to the terminal glucuronate residue forms chondroitin"
Reactome:R-HSA-1971487 "CHPF,CHSY3 transfer GalNAc to chondroitin"
Reactome:R-HSA-3595176 "Defective CHSY1 does not transfer GalNAc to chondroitin"
Reactome:R-HSA-9632033 "CHSY1 transfers GalNAc to chondroitin"