FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity

ID (Ontology)

GO:0047238 (Gene Ontology)

Definition

Catalysis of the reaction: D-glucuronyl-N-acetyl-1,3-beta-D-galactosaminylproteoglycan + UDP-N-acetylgalactosamine = N-acetyl-D-galactosaminyl-1,4-beta-D-glucuronyl-N-acetyl-1,3-beta-D-galactosaminylproteoglycan + UDP.[ EC:2 ]

Also Known As

"glucuronyl-N-acetylgalactosaminylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity" ; "glucuronyl-N-acetylgalactosaminylproteoglycan beta-1,4-N-acetylgalactosaminyltransferase activity" ; "N-acetylgalactosaminyltransferase II activity"

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

Choose a record type to view annotations for this term and its child terms. Direct annotations and full annotation statements below also provide HitList buttons.

Results list data from multiple species. Choose a record type above to open its HitList.

Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_MOLECULAR_FUNCTION

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Gene Groups	Genes
glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity (all annotations which use CV term, excluding "NOT" statements)
enables \| glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity	--

Spanning Tree (Parents/Children)

UDP-glycosyltransferase activity__
hexosyltransferase activity_______|
                                  acetylgalactosaminyltransferase activity
                                   |__glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity  4 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	acetylgalactosaminyltransferase activity
Part of
Synonyms & Secondary IDs
Synonyms
	"chondroitin synthase activity" RELATED[ EC:2 ] "glucuronyl-N-acetylgalactosaminylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity" EXACT "glucuronyl-N-acetylgalactosaminylproteoglycan beta-1,4-N-acetylgalactosaminyltransferase activity" EXACT "N-acetylgalactosaminyltransferase II activity" EXACT "UDP-N-acetyl-D-galactosamine:beta-D-glucuronosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity" RELATED[ EC:2 ] "UDP-N-acetyl-D-galactosamine:D-glucuronyl-N-acetyl-1,3-beta-D-galactosaminylproteoglycan beta-1,4-N-acetylgalactosaminyltransferase activity" RELATED[ EC:2 ] "uridine diphosphoacetylgalactosamine-chondroitin acetylgalactosaminyltransferase II activity" RELATED[ EC:2 ]
Secondary IDs

External Crossreferences & Linkouts
	EC:2.4.1.175 MetaCyc:RXN-16325 Reactome:R-HSA-1971482 "CSGALNACTs transfer GalNAc to CS linker glycan" Reactome:R-HSA-1971487 "Chondroitin polymerase complex transfers GalNAc to CS chain" Reactome:R-HSA-3595176 "Defective CHSY1 does not transfer GalNAc to chondroitin" Reactome:R-HSA-9632033 "CSGALNACTs transfer GalNAc to CS chain"