FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term nucleoside triphosphate diphosphatase activity ID (Ontology) GO:0047429 (Gene Ontology)
Definition Catalysis of the reaction: a nucleoside triphosphate + H2O = a nucleotide + H+ + diphosphate.[ EC:3 ]
Also Known As"nucleoside-triphosphate diphosphatase activity" ; "nucleoside-triphosphate diphosphohydrolase activity" ; "nucleoside-triphosphate pyrophosphatase activity"
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Genes (FBgn)GO_MOLECULAR_FUNCTION
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 nucleoside triphosphate diphosphatase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | nucleoside triphosphate diphosphatase activity       --
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  hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
   |__pyrophosphatase activity
       |__nucleoside triphosphate diphosphatase activity  4 rec.
           |__2-hydroxy-ATP hydrolase activity
           |__2-hydroxy-dATP hydrolase activity
           |__8-oxo-(d)RTP hydrolase activity
           |__8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity
           |__8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity
           |__ATP diphosphatase activity
           |__dATP diphosphatase activity
           |__dCTP diphosphatase activity
           |__dGTP diphosphatase activity
           |__dITP diphosphatase activity 1 rec.
           |__dTTP diphosphatase activity
           |__dUTP diphosphatase activity 1 rec.
           |__GTP diphosphatase activity
           |__ITP diphosphatase activity 1 rec.
           |__UTP diphosphatase activity
           |__XTP diphosphatase activity 1 rec.
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Is a pyrophosphatase activity
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Synonyms
  • "nucleoside-triphosphate diphosphatase activity" EXACT
    "nucleoside-triphosphate diphosphohydrolase activity" EXACT[ EC:3 ]
    "nucleoside-triphosphate pyrophosphatase activity" EXACT[ EC:3 ]
Secondary IDs
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EC:3.6.1.9
MetaCyc:NUCLEOTIDE-PYROPHOSPHATASE-RXN
Reactome:R-HSA-9755030 "ITPA dimer dephosphorylates RBV-TP to RBV-MP"
RHEA:23996
RHEA:27762
RHEA:44644
RHEA:58732
RHEA:58736
RHEA:58740
RHEA:58744