FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term N-acylneuraminate-9-phosphate synthase activity ID (Ontology) GO:0047444 (Gene Ontology)
Definition Catalysis of the reaction: H2O + phosphoenolpyruvate + N-acyl-D-mannosamine 6-phosphate = phosphate + N-acylneuraminate 9-phosphate.[ EC:2 ]
Also Known As"N-acetylneuraminic acid phosphate synthase activity"
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Genes (FBgn)GO_MOLECULAR_FUNCTION
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 N-acylneuraminate-9-phosphate synthase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | N-acylneuraminate-9-phosphate synthase activity
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  transferase activity
   |__transferase activity, transferring alkyl or aryl (other than methyl) groups
       |__N-acylneuraminate-9-phosphate synthase activity  1 rec.
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Is a transferase activity, transferring alkyl or aryl (other than methyl) groups
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Synonyms
  • "N-acetylneuraminate 9-phosphate lyase activity" RELATED[ EC:2 ]
    "N-acetylneuraminate 9-phosphate sialic acid 9-phosphate synthase activity" RELATED[ EC:2 ]
    "N-acetylneuraminate 9-phosphate synthetase activity" RELATED[ EC:2 ]
    "N-acetylneuraminic acid phosphate synthase activity" EXACT
    "N-acylneuraminate-9-phosphate pyruvate-lyase (pyruvate-phosphorylating) activity" RELATED[ EC:2 ]
    "phosphoenolpyruvate:N-acyl-D-mannosamine-6-phosphate 1-(2-carboxy-2-oxoethyl)transferase activity" RELATED[ EC:2 ]
    "sialic acid 9-phosphate synthetase activity" RELATED[ EC:2 ]
Secondary IDs
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EC:2.5.1.57
MetaCyc:RXN-9988
Reactome:R-HSA-4084976 "NANS converts ManNAc-6-P to Neu5Ac-9-P"
RHEA:13421
RHEA:80835