FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term ADP-ribose diphosphatase activity ID (Ontology) GO:0047631 (Gene Ontology)
Definition Catalysis of the reaction: ADP-ribose + H2O = AMP + D-ribose 5-phosphate.[ EC:3 ]
Also Known As"adenosine diphosphoribose pyrophosphatase activity" ; "ADPR-PPase activity"
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Genes (FBgn)GO_MOLECULAR_FUNCTION
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 ADP-ribose diphosphatase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | ADP-ribose diphosphatase activity       --
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  hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
   |__pyrophosphatase activity
       |__ADP-ribose diphosphatase activity  4 rec.
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Is a pyrophosphatase activity
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Synonyms
  • "adenosine diphosphoribose pyrophosphatase activity" EXACT
    "ADP-ribose ribophosphohydrolase activity" RELATED[ EC:3 ]
    "ADPR-PPase activity" EXACT
    "ADPribose diphosphatase activity" RELATED[ EC:3 ]
    "ADPribose pyrophosphatase activity" RELATED[ EC:3 ]
Secondary IDs
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EC:3.6.1.13
MetaCyc:RXN0-1441
Reactome:R-HSA-2393939 "Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP"
Reactome:R-HSA-2393954 "Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP"
Reactome:R-HSA-5696049 "ADPRM hydrolyses ADP-ribose to R5P and AMP"
RHEA:10412