FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

hydroxyacid-oxoacid transhydrogenase activity

ID (Ontology)

GO:0047988 (Gene Ontology)

Definition

Catalysis of the reaction: (S)-3-hydroxybutanoate + 2-oxoglutarate = acetoacetate + (R)-2-hydroxyglutarate.[ EC:1 ]

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Results list data from multiple species. Choose a record type above to open its HitList.

Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_MOLECULAR_FUNCTION

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
hydroxyacid-oxoacid transhydrogenase activity (all annotations which use CV term, excluding "NOT" statements)
enables \| hydroxyacid-oxoacid transhydrogenase activity

Spanning Tree (Parents/Children)

  oxidoreductase activity
   |__oxidoreductase activity, acting on CH-OH group of donors
       |__hydroxyacid-oxoacid transhydrogenase activity  1 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	oxidoreductase activity, acting on CH-OH group of donors
Part of
Synonyms & Secondary IDs
Synonyms
	"(S)-3-hydroxybutanoate:2-oxoglutarate oxidoreductase activity" RELATED[ EC:1 ] "transhydrogenase, hydroxy acid-oxo acid" RELATED[ EC:1 ]
Secondary IDs

External Crossreferences & Linkouts
	EC:1.1.99.24 MetaCyc:HYDROXYACID-OXOACID-TRANSHYDROGENASE-RXN Reactome:R-HSA-880002 "(R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate" Reactome:R-HSA-880033 "2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde"