FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
Help Close All Open All
General Information
Term receptor ligand activity ID (Ontology) GO:0048018 (Gene Ontology)
Definition The activity of a gene product that interacts with a receptor to effect a change in the activity of the receptor. Ligands may be produced by the same cell that expresses the receptor. Ligands may also be expressed at the plasma membrane of an adjacent cell (e.g. Notch ligands) or be secreted and diffuse extracellularly from their point of origin to the receiving cell (e.g. interleukins).
Also Known As "signaling receptor ligand activity"
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
    Results list data from multiple species. Click on a button above and use the 'Filter by species' options on the resulting HitList to retrieve species-specific data.
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_CELLULAR_COMPONENT       3
Genes (FBgn)  GO_MOLECULAR_FUNCTION      45
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 receptor ligand activity (all annotations which use CV term, excluding "NOT" statements)      10     45
     enables | receptor ligand activity       --      45
Spanning Tree (Parents/Children)
Only view relationship: 
signaling receptor regulator activity__
molecular function activator activity__|
                                       signaling receptor activator activity
                                        |__receptor ligand activity  130 rec.
                                            |__chemoattractant activity 2 rec.
                                            |   |__chemoattractant activity involved in axon guidance
                                            |__chemorepellent activity 5 rec.
                                            |__cytokine activity 28 rec.
                                            |   |__chemokine activity 1 rec.
                                            |__death receptor agonist activity
                                            |__growth factor activity 22 rec.
                                            |__hormone activity 48 rec.
                                            |   |__corticotropin-releasing hormone activity
                                            |   |__digestive hormone activity
                                            |   |__diuretic hormone activity 4 rec.
                                            |   |__follicle-stimulating hormone activity
                                            |   |__gonadotropin hormone-releasing hormone activity
                                            |   |__growth hormone activity
                                            |   |__growth hormone-releasing hormone activity
                                            |   |__melanin-concentrating hormone activity
                                            |   |__melanocyte-stimulating hormone activity
                                            |   |__myoinhibitory hormone activity 1 rec.
                                            |   |__myostimulatory hormone activity 2 rec.
                                            |   |__neuropeptide hormone activity(+) 30 rec.
                                            |   |__pituitary adenylate cyclase activating polypeptide activity
                                            |   |__thyrotropin-releasing hormone activity
                                            |__morphogen activity 5 rec.
                                            |__neuropeptide activity 33 rec.
                                            |   |__neuropeptide hormone activity(+) 30 rec.
                                            |__opioid peptide activity
                                            |__pathogen-derived receptor ligand activity
                                            |__pheromone activity
                                                |__competence pheromone activity
                                                |__mating pheromone activity
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a signaling receptor activator activity
Part of
hide Synonyms & Secondary IDs
Synonyms
  • "agonist" BROAD
    "receptor agonist activity" RELATED
    "signaling molecule" BROAD
    "signaling receptor ligand activity" EXACT
Secondary IDs
hide External Crossreferences & Linkouts
Reactome:R-HSA-381612 "GLP1R binds GLP1"
Reactome:R-HSA-8848663 "ADIPOQ trimer binds ADIPOR dimers"