FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term sphingomyelin phosphodiesterase D activity ID (Ontology) GO:0050290 (Gene Ontology)
Definition Catalysis of the reaction: H2O + sphingomyelin = ceramide 1-phosphate + choline + H+.[ EC:3 ]
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 Genes
 sphingomyelin phosphodiesterase D activity (all annotations which use CV term, excluding "NOT" statements)
     enables | sphingomyelin phosphodiesterase D activity
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phosphoric diester hydrolase activity__
sphingophospholipase activity__________|
                                       sphingomyelin phosphodiesterase activity
                                        |__sphingomyelin phosphodiesterase D activity  1 rec.
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Is a sphingomyelin phosphodiesterase activity
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Synonyms
  • "sphingomyelin ceramide-phosphohydrolase activity" RELATED[ EC:3 ]
    "sphingomyelinase D" RELATED[ EC:3 ]
Secondary IDs
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EC:3.1.4.41
KEGG_REACTION:R02542
MetaCyc:SPHINGOMYELIN-PHOSPHODIESTERASE-D-RXN
RHEA:20984