FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term sphingosine N-acyltransferase activity ID (Ontology) GO:0050291 (Gene Ontology)
Definition Catalysis of the reaction: acyl-CoA + sphingosine = CoA + N-acylsphingosine.[ EC:2 PubMed:12069845 ]
Also Known As"ceramide synthase activity" ; "dihydroceramide synthase activity"
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 sphingosine N-acyltransferase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | sphingosine N-acyltransferase activity
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  acyltransferase activity
   |__acyltransferase activity, transferring groups other than amino-acyl groups
       |__sphingosine N-acyltransferase activity  1 rec.
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Is a acyltransferase activity, transferring groups other than amino-acyl groups
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Synonyms
  • "acyl-CoA:sphingosine N-acyltransferase activity" RELATED[ EC:2 ]
    "ceramide synthase activity" EXACT
    "ceramide synthetase activity" RELATED[ EC:2 ]
    "dihydroceramide synthase activity" EXACT
    "sphingosine acyltransferase activity" RELATED[ EC:2 ]
Secondary IDs
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EC:2.3.1.24
MetaCyc:SPHINGOSINE-N-ACYLTRANSFERASE-RXN
Reactome:R-HSA-428185 "Ceramide synthases transfer acyl-CoA onto sphingoid"
RHEA:23768
RHEA:36687
RHEA:36691
RHEA:37111
RHEA:37115
RHEA:37123
RHEA:45284
RHEA:64044