FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity ID (Ontology) GO:0050510 (Gene Ontology)
Definition Catalysis of the reaction: N-acetyl-beta-D-galactosaminyl-(1,4)-beta-D-glucuronosyl-proteoglycan + UDP-alpha-D-glucuronate = beta-D-glucuronosyl-(1,3)-N-acetyl-beta-D-galactosaminyl-(1,4)-beta-D-glucuronosyl-proteoglycan + UDP.[ EC:2 ]
Also Known As "N-acetylgalactosaminyl-proteoglycan 3-b-glucuronosyltransferase activity"
Comment
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       2
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 Full annotation statements 
Relevant FlyBase reports
 Genes
 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity (all annotations which use CV term, excluding "NOT" statements)       2
     enables | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity       2
Spanning Tree (Parents/Children)
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UDP-glycosyltransferase activity__
hexosyltransferase activity_______|
                                  glucuronosyltransferase activity
                                   |__N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity  2 rec.
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Is a glucuronosyltransferase activity
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Synonyms
  • "alpha-D-glucuronate:N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-glucuronosyl-proteoglycan 3-beta-glucuronosyltransferase activity" RELATED[ EC:2 ]
    "chondroitin glucuronyltransferase II activity" RELATED[ EC:2 ]
    "N-acetylgalactosaminyl-proteoglycan 3-b-glucuronosyltransferase activity" EXACT
Secondary IDs
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EC:2.4.1.226
MetaCyc:RXN-16324
Reactome:R-HSA-1971491 "CHPF,CHPF2,CHSY3 transfer GlcA to chondroitin"
Reactome:R-HSA-3595178 "Defective CHSY1 does not transfer GlcA to chondroitin"
Reactome:R-HSA-9632034 "CHSY1 transfers GlcA to chondroitin"