FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term CARD domain binding ID (Ontology) GO:0050700 (Gene Ontology)
Definition Binding to a CARD (N-terminal caspase recruitment) domain, a protein-protein interaction domain that belongs to the death domain-fold superfamily. These protein molecule families are similar in structure with each consisting of six or seven anti-parallel alpha-helices that form highly specific homophilic interactions between signaling partners. CARD exists in the N-terminal prodomains of several caspases and in apoptosis-regulatory proteins and mediates the assembly of CARD-containing proteins that participate in activation or suppression of CARD carrying members of the caspase family.[ PubMed:12054670 ]
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       3
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 CARD domain binding (all annotations which use CV term, excluding "NOT" statements)       3
     enables | CARD domain binding       3
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   |__protein domain specific binding
       |__CARD domain binding  3 rec.
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