FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

T cell receptor signaling pathway

ID (Ontology)

GO:0050852 (Gene Ontology)

Definition

The series of molecular signals initiated by the cross-linking of an antigen receptor on a T cell.

Also Known As

"T lymphocyte receptor signaling pathway" ; "T lymphocyte receptor signalling pathway" ; "T-cell receptor signaling pathway" (for all, see Synonyms field below)

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_BIOLOGICAL_PROCESS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
T cell receptor signaling pathway (all annotations which use CV term, excluding "NOT" statements)
involved_in \| T cell receptor signaling pathway

Spanning Tree (Parents/Children)

  immune response-activating cell surface receptor signaling pathway
   |__antigen receptor-mediated signaling pathway
       |__T cell receptor signaling pathway  3 rec.
           |__regulation of T cell receptor signaling pathway
           |   |__negative regulation of T cell receptor signaling pathway(+)
           |   |__positive regulation of T cell receptor signaling pathway
           |__termination of T cell signal transduction

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	antigen receptor-mediated signaling pathway
Part of
Synonyms & Secondary IDs
Synonyms
	"T lymphocyte receptor signaling pathway" EXACT "T lymphocyte receptor signalling pathway" EXACT "T-cell receptor signaling pathway" EXACT "T-cell receptor signalling pathway" EXACT "T-lymphocyte receptor signaling pathway" EXACT "T-lymphocyte receptor signalling pathway" EXACT "TCR signaling pathway" EXACT
Secondary IDs

External Crossreferences & Linkouts
	Reactome:R-HSA-202403 "TCR signaling"