FB2026_03 , released September 17, 2026
FB2026_03 , released September 17, 2026
CV Term Report
Help Close All Open All
General Information
Term dioxygenase activity ID (Ontology) GO:0051213 (Gene Ontology)
Definition Catalysis of the incorporation of both atoms of molecular oxygen (O2) into the substrate.[ PubMed:1444267 ]
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS

Choose a record type to view annotations for this term and its child terms. Direct annotations and full annotation statements below also provide HitList buttons.

    • Results list data from multiple species. Choose a record type above to open its HitList.
Direct annotations: records annotated with this exact term (child terms are NOT included)
There are no annotations using this term.
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Gene Groups
 dioxygenase activity (all annotations which use CV term, excluding "NOT" statements)
Spanning Tree (Parents/Children)
Only view relationship:
Vocabulary search 
  catalytic activity
   |__oxidoreductase activity
       |__dioxygenase activity  71 rec.
           |__2-oxoglutarate-dependent dioxygenase activity 61 rec.
           |   |__2'-deoxymugineic-acid 2'-dioxygenase activity
           |   |__2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity
           |   |__2-oxoglutarate, L-arginine oxygenase (succinate-forming) activity
           |   |__2-oxoglutarate-dependent tRNA 5-methylcytidine formyltransferase activity 1 rec.
           |   |__4-coumaroyl 2'-hydroxylase activity
           |   |__[protein]-asparagine 3-dioxygenase activity
           |   |__alpha-ketoglutarate-dependent xanthine dioxygenase activity
           |   |__broad specificity oxidative DNA demethylase activity 1 rec.
           |   |__clavaminate synthase activity
           |   |__codeine O-demethylase activity
           |   |__deacetoxycephalosporin-C hydroxylase activity
           |   |__deoxyuridine 1'-dioxygenase activity
           |   |__deoxyuridine 2'-dioxygenase activity
           |   |__desacetoxyvindoline 4-hydroxylase activity
           |   |__DIBOA-glucoside oxygenase activity
           |   |__DNA 5-methylcytosine dioxygenase activity
           |   |__DNA N6-methyladenine demethylase activity 2 rec.
           |   |__flavanone 3-dioxygenase activity
           |   |__gamma-butyrobetaine dioxygenase activity 4 rec.
           |   |__gibberellin 2-beta-dioxygenase activity
           |   |__gibberellin 3-beta-dioxygenase activity
           |   |__gibberellin 20-oxidase activity
           |   |__glutarate dioxygenase activity
           |   |__histone H3K4me/H3K4me2/H3K4me3 demethylase activity 3 rec.
           |   |__histone H3K9me/H3K9me2 demethylase activity 1 rec.
           |   |__histone H3K9me2/H3K9me3 demethylase activity 2 rec.
           |   |__histone H3K27me2/H3K27me3 demethylase activity 2 rec.
           |   |__histone H3K36 demethylase activity(+) 5 rec.
           |   |__histone H3K56me2/H3K56me3 demethylase activity 1 rec.
           |   |__histone H3R2 demethylase activity 1 rec.
           |   |__histone H4K20 demethylase activity 1 rec.
           |   |__histone H4R3 demethylase activity 2 rec.
           |   |__hyoscyamine (6S)-dioxygenase activity
           |   |__L-gamma-glutamyl-L-propargylglycine hydroxylase activity
           |   |__L-isoleucine 4-hydroxylase activity
           |   |__mugineic-acid 3-dioxygenase activity
           |   |__oxidative RNA demethylase activity(+) 1 rec.
           |   |__peptidyl-arginine 3-dioxygenase activity 1 rec.
           |   |__peptidyl-aspartic acid 3-dioxygenase activity 1 rec.
           |   |__peptidyl-histidine dioxygenase activity
           |   |__peptidyl-lysine 3-dioxygenase activity 1 rec.
           |   |__peptidyl-lysine 4-dioxygenase activity 1 rec.
           |   |__peptidyl-lysine 5-dioxygenase activity 1 rec.
           |   |__peptidyl-proline dioxygenase activity(+) 28 rec.
           |   |__phytanoyl-CoA dioxygenase activity
           |   |__procollagen-lysine 5-dioxygenase activity 1 rec.
           |   |__proline 3-hydroxylase activity
           |   |__scopoletin 8-hydroxylase activity
           |   |__sulfonate dioxygenase activity
           |   |__taurine dioxygenase activity
           |   |__thebaine 6-O-demethylase activity
           |   |__thymine dioxygenase activity
           |   |__trimethyllysine dioxygenase activity 1 rec.
           |   |__tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine37-C2)-hydroxylase activity
           |__3-butenylglucosinolate 2-hydroxylase activity
           |__oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor
           |   |__2-aminobenzenesulfonate 2,3-dioxygenase activity
           |   |__2-halobenzoate 1,2-dioxygenase activity
           |   |__2-hydroxyquinoline 5,6-dioxygenase activity
           |   |__3,4-dichlorobenzoate-4,5-oxygenase activity
           |   |__3-chlorobenzoate-3,4-oxygenase activity
           |   |__3-phenylpropionate dioxygenase activity
           |   |__4-chlorophenylacetate 3,4-dioxygenase activity
           |   |__4-sulfobenzoate 3,4-dioxygenase activity
           |   |__anthranilate 1,2-dioxygenase (deaminating, decarboxylating) activity
           |   |__benzene 1,2-dioxygenase activity
           |   |__benzoate 1,2-dioxygenase activity
           |   |__biphenyl 2,3-dioxygenase activity
           |   |__carbazole 1,9a-dioxygenase [NAD(P)H] activity
           |   |__dibenzofuran 4,4a-dioxygenase activity
           |   |__naphthalene 1,2-dioxygenase activity
           |   |__nitric oxide dioxygenase [NAD(P)H] activity
           |   |__p-cumate 2,3-dioxygenase activity
           |   |__phthalate 4,5-dioxygenase activity
           |   |__terephthalate 1,2-dioxygenase activity
           |   |__toluene dioxygenase activity
           |   |__trihydroxytoluene dioxygenase activity
           |__oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 8 rec.
               |__1,2-dihydroxynaphthalene dioxygenase activity
               |__1-hydroxy-2-naphthoate 1,2-dioxygenase activity
               |__2,3-dihydroxy-p-cumate dioxygenase activity
               |__2,3-dihydroxybenzoate 2,3-dioxygenase activity
               |__2,3-dihydroxybenzoate 3,4-dioxygenase activity
               |__2,3-dihydroxybiphenyl 1,2-dioxygenase activity
               |__2,3-dihydroxyindole 2,3-dioxygenase activity
               |__2,4'-dihydroxyacetophenone dioxygenase activity
               |__2,5-dihydroxypyridine 5,6-dioxygenase activity
               |__3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-dioxygenase activity
               |__3,4-dihydroxyphenylacetate 2,3-dioxygenase activity
               |__3-carboxyethylcatechol 2,3-dioxygenase activity
               |__3-hydroxy-2-methylquinolin-4-one 2,4-dioxygenase activity
               |__3-hydroxy-4-oxoquinoline 2,4-dioxygenase activity
               |__3-hydroxyanthranilate 3,4-dioxygenase activity
               |__4-hydroxymandelate synthase activity
               |__4-hydroxyphenylpyruvate dioxygenase activity 1 rec.
               |__5,6-dimethylbenzimidazole synthase activity
               |__7,8-dihydroxykynurenate 8,8a-dioxygenase activity
               |__9-cis-10'-apo-beta-carotenal cleavage oxygenase activity
               |__9-cis-beta-carotene 9',10'-cleavage oxygenase activity
               |__acetylacetone-cleaving enzyme activity
               |__acireductone dioxygenase (Ni2+-requiring) activity 1 rec.
               |__acireductone dioxygenase [iron(II)-requiring] activity 1 rec.
               |__all-trans-8'-apo-beta-carotenal 15,15'-oxygenase activity
               |__all-trans-beta-apo-10'-carotenal cleavage oxygenase activity
               |__apo-beta-carotenoid-14',13'-dioxygenase activity
               |__arachidonate 5-lipoxygenase activity
               |__arachidonate 8(R)-lipoxygenase activity
               |__arachidonate 8(S)-lipoxygenase activity
               |__arachidonate 12(R)-lipoxygenase activity
               |__arachidonate 12(S)-lipoxygenase activity
               |__arachidonate 15-lipoxygenase activity
               |__beta,beta-carotene-9',10'-cleaving oxygenase activity
               |__beta-carotene 15,15'-dioxygenase activity 1 rec.
               |__biphenyl-2,3-diol 1,2-dioxygenase activity
               |__caffeate 3,4-dioxygenase activity
               |__carotenoid dioxygenase activity(+) 1 rec.
               |__catechol 1,2-dioxygenase activity
               |__catechol 2,3-dioxygenase activity
               |__chloridazon-catechol dioxygenase activity
               |__chlorite O2-lyase activity
               |__cysteamine dioxygenase activity 1 rec.
               |__cysteine dioxygenase activity 1 rec.
               |__fatty acid alpha-dioxygenase activity
               |__gallate dioxygenase activity
               |__gentisate 1,2-dioxygenase activity
               |__homogentisate 1,2-dioxygenase activity 1 rec.
               |__hydroxyquinol 1,2-dioxygenase activity
               |__indole 2,3-dioxygenase activity
               |__indoleamine 2,3-dioxygenase activity
               |__L-tryptophan 2,3-dioxygenase activity 1 rec.
               |__lignostilbene alpha beta-dioxygenase activity
               |__linoleate 8R-lipoxygenase activity
               |__linoleate 9S-lipoxygenase activity
               |__linoleate 11-lipoxygenase activity
               |__linoleate 13S-lipoxygenase activity
               |__linolenate 9R-lipoxygenase activity
               |__protocatechuate 3,4-dioxygenase activity
               |__protocatechuate 4,5-dioxygenase activity
               |__pyrogallol 1,2-oxygenase activity
               |__quercetin 2,3-dioxygenase activity
               |__questin hydroquinone dioxygenase activity
               |__resveratrol dioxygenase activity
               |__stizolobate synthase activity
               |__stizolobinate synthase activity
               |__sulfur dioxygenase activity 1 rec.
               |__sulfur oxygenase/reductase activity
               |__violaxanthin oxygenase activity
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a oxidoreductase activity
Part of
hide Synonyms & Secondary IDs
Synonyms
Secondary IDs
hide External Crossreferences & Linkouts
Reactome:R-HSA-112120 "Oxidative demethylation of 3-meC damaged DNA by ALKBH2"
Reactome:R-HSA-112121 "Oxidative dealkylation of 1-etA damaged DNA By ALKBH2"
Reactome:R-HSA-112124 "Oxidative demethylation of 3-meC damaged DNA By ALKBH3"
Reactome:R-HSA-112125 "Oxidative dealkylation of 1-EtA damaged DNA by ABH3"