FB2026_03 , released September 17, 2026
FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term chromosome separation ID (Ontology) GO:0051304 (Gene Ontology)
Definition The cell cycle process in which paired chromosomes are detached from each other. Chromosome separation begins with the release of cohesin complexes from chromosomes; in budding yeast, this includes the cleavage of cohesin complexes along the chromosome arms, followed by the separation of the centromeric regions. Chromosome separation also includes formation of chromatid axes mediated by condensins, and ends with the disentangling of inter-sister catenation catalyzed by topoisomerase II (topo II).[ PubMed:20352243 ]
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Genes (FBgn)GO_BIOLOGICAL_PROCESS
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 chromosome separation (all annotations which use CV term, excluding "NOT" statements)
     involved_in | chromosome separation       --
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cell cycle
 |__cell cycle process______
cellular process            |
 |__cell cycle process______|
cell cycle process          |
 |__chromosome segregation__|
                            chromosome separation  38 rec.
                             |__centromere separation
                             |   |__meiotic sister chromatid centromere separation
                             |__meiotic chromosome separation 5 rec.
                             |   |__female meiosis chromosome separation
                             |   |__male meiosis chromosome separation 1 rec.
                             |   |__meiotic sister chromatid separation(+)
                             |   |__regulation of meiotic chromosome separation(+) 2 rec.
                             |__mitotic sister chromatid separation 28 rec.
                             |   |__mitotic sister chromatid arm separation(+)
                             |   |__regulation of mitotic sister chromatid separation(+) 23 rec.
                             |__regulation of chromosome separation 24 rec.
                                 |__negative regulation of chromosome separation(+) 14 rec.
                                 |__positive regulation of chromosome separation(+) 10 rec.
                                 |__regulation of meiotic chromosome separation(+) 2 rec.
                                 |__regulation of mitotic sister chromatid separation(+) 23 rec.
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Is a cell cycle process
Part of chromosome segregation
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