FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

alpha-actinin binding

ID (Ontology)

GO:0051393 (Gene Ontology)

Definition

Binding to alpha-actinin, one of a family of proteins that cross-link F-actin as antiparallel homodimers. Alpha-actinin has a molecular mass of 93-103 KDa; at the N-terminus there are two calponin homology domains, at the C-terminus there are two EF-hands. These two domains are connected by the rod domain. This domain is formed by triple-helical spectrin repeats.[ PubMed:10984498 PubMed:11699871 PubMed:15014165 ]

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_MOLECULAR_FUNCTION

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
alpha-actinin binding (all annotations which use CV term, excluding "NOT" statements)
enables \| alpha-actinin binding

Spanning Tree (Parents/Children)

  cytoskeletal protein binding
   |__actinin binding
       |__alpha-actinin binding  5 rec.
           |__muscle alpha-actinin binding 4 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	actinin binding
Part of
Synonyms & Secondary IDs
Synonyms
	"alpha-actinin 1 binding" NARROW "alpha-actinin 4 binding" NARROW "nonmuscle alpha-actinin binding" NARROW
Secondary IDs

External Crossreferences & Linkouts