FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term intracellular pH reduction ID (Ontology) GO:0051452 (Gene Ontology)
Definition Any process that reduces the internal pH of a cell, corresponding to an increase in hydrogen ion concentration.
Also Known As"cell pH reduction" ; "cellular acidification" ; "reduction of cellular pH" (for all, see Synonyms field below)
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Genes (FBgn)GO_BIOLOGICAL_PROCESS
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 intracellular pH reduction (all annotations which use CV term, excluding "NOT" statements)
     involved_in | intracellular pH reduction
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regulation of pH_____________________________
intracellular monoatomic cation homeostasis__|
regulation of biological quality_____________|
                                             regulation of intracellular pH
                                              |__intracellular pH reduction  24 rec.
                                                  |__endosomal lumen acidification 2 rec.
                                                  |__Golgi lumen acidification
                                                  |__melanosomal lumen acidification
                                                  |__phagosome acidification
                                                  |   |__phagosome acidification involved in apoptotic cell clearance
                                                  |__vacuolar acidification 20 rec.
                                                      |__lysosomal lumen acidification 3 rec.
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Is a regulation of intracellular pH
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Synonyms
  • "cell pH reduction" EXACT
    "cellular acidification" EXACT
    "intracellular acidification" RELATED
    "reduction of cellular pH" EXACT
    "reduction of pH in cell" EXACT
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