FB2026_03 , released September 17, 2026
CV Term Report
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Term protein maturation ID (Ontology) GO:0051604 (Gene Ontology)
Definition Any process leading to the attainment of the full functional capacity of a protein.
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Genes (FBgn)GO_BIOLOGICAL_PROCESS
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 protein maturation (all annotations which use CV term, excluding "NOT" statements)
     involved_in | protein maturation
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macromolecule biosynthetic process
 |__gene expression______________
macromolecule metabolic process  |
 |__protein metabolic process____|
primary metabolic process        |
 |__protein metabolic process____|
                                 protein maturation  347 rec.
                                  |__attachment of GPI anchor to protein 7 rec.
                                  |__CAAX-box protein maturation 7 rec.
                                  |   |__CAAX-box protein processing 7 rec.
                                  |__GPI anchor remodelling 4 rec.
                                  |__GPI anchored protein biosynthesis 44 rec.
                                  |   |__attachment of GPI anchor to protein 7 rec.
                                  |   |__GPI anchor biosynthetic process 35 rec.
                                  |   |__GPI anchor remodelling 4 rec.
                                  |__N-terminal protein amino acid acetylation 11 rec.
                                  |   |__N-terminal peptidyl-aspartic acid acetylation 1 rec.
                                  |   |__N-terminal peptidyl-glutamic acid acetylation 1 rec.
                                  |   |__N-terminal peptidyl-glutamine acetylation
                                  |   |__N-terminal peptidyl-lysine acetylation(+)
                                  |   |__N-terminal peptidyl-methionine acetylation(+) 1 rec.
                                  |__peptide pheromone maturation 1 rec.
                                  |__peptidyl-hypusine biosynthetic process 3 rec.
                                  |__protein activation cascade 29 rec.
                                  |   |__blood coagulation, common pathway(+)
                                  |   |__blood coagulation, extrinsic pathway(+)
                                  |   |__blood coagulation, fibrin clot formation(+)
                                  |   |__blood coagulation, intrinsic pathway(+)
                                  |   |__kinin cascade(+)
                                  |   |__regulation of protein activation cascade(+) 5 rec.
                                  |   |__Toll receptor ligand protein activation cascade(+) 29 rec.
                                  |__protein folding 149 rec.
                                  |   |__'de novo' protein folding(+) 3 rec.
                                  |   |__protein folding in endoplasmic reticulum(+) 4 rec.
                                  |   |__protein refolding(+) 34 rec.
                                  |   |__regulation of protein folding(+)
                                  |__protein lipoylation 2 rec.
                                  |__protein processing 91 rec.
                                  |   |__activation of plasma proteins involved in acute inflammatory response
                                  |   |__CAAX-box protein processing 7 rec.
                                  |   |__dibasic protein processing(+)
                                  |   |__mitochondrial protein processing 5 rec.
                                  |   |__Notch receptor processing, ligand-independent
                                  |   |__protein autoprocessing 6 rec.
                                  |   |__protein processing in phagocytic vesicle(+)
                                  |   |__protein splicing(+) 1 rec.
                                  |   |__regulation of protein processing(+) 4 rec.
                                  |   |__signaling receptor ligand precursor processing(+) 20 rec.
                                  |   |__vacuolar protein processing
                                  |   |__zymogen activation(+) 8 rec.
                                  |__protein-tetrapyrrole linkage
                                  |   |__protein-bilin linkage(+)
                                  |   |__protein-heme linkage(+)
                                  |__regulation of protein maturation 9 rec.
                                      |__negative regulation of protein maturation(+) 6 rec.
                                      |__positive regulation of protein maturation(+) 1 rec.
                                      |__regulation of N-terminal peptidyl-lysine acetylation(+)
                                      |__regulation of N-terminal peptidyl-methionine acetylation(+)
                                      |__regulation of protein activation cascade(+) 5 rec.
                                      |__regulation of protein processing(+) 4 rec.
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Is a protein metabolic process
Part of gene expression
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Reactome:R-HSA-9918432 "Maturation of DENV proteins"