FB2026_03 , released September 17, 2026
FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term protein methylesterase activity ID (Ontology) GO:0051723 (Gene Ontology)
Definition Catalysis of the reaction: protein amino acid methyl ester + H2O = protein amino acid + methanol.
Also Known As "protein carboxylic ester hydrolase activity"
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 protein methylesterase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | protein methylesterase activity
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catalytic activity
 |__catalytic activity, acting on a protein__
hydrolase activity, acting on ester bonds    |
 |__carboxylic ester hydrolase activity______|
                                             protein methylesterase activity  1 rec.
                                              |__prenylcysteine methylesterase activity
                                              |__protein-glutamate methylesterase activity
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Is a carboxylic ester hydrolase activity
catalytic activity, acting on a protein
Part of
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Synonyms
  • "PME activity" RELATED[ EC:2 ]
    "protein carboxyl methylesterase activity" RELATED[ EC:2 ]
    "protein carboxylic ester hydrolase activity" EXACT
    "protein methyl-esterase activity" RELATED[ EC:2 ]
Secondary IDs
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EC:3.1.1.89
MetaCyc:RXN-12322
Reactome:R-HSA-5367022 "DPH7 hydrolyzes a methyl group on Me-diphthine EEF2"
Reactome:R-HSA-8856951 "PP2A demethylation by PPME1"
RHEA:48548