FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity ID (Ontology) GO:0051800 (Gene Ontology)
Definition Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 4-phosphate + phosphate.[ PubMed:9811831 ]
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Genes (FBgn)GO_MOLECULAR_FUNCTION
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 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity
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  phosphatidylinositol bisphosphate phosphatase activity
   |__phosphatidylinositol-3,4-bisphosphate phosphatase activity
       |__phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity  1 rec.
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Is a phosphatidylinositol-3,4-bisphosphate phosphatase activity
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Synonyms
  • "PTEN activity" BROAD
Secondary IDs
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Reactome:R-HSA-1676149 "PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane"
Reactome:R-HSA-1676204 "PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane"